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Preparation of amines: Gabriel, Hofmann bromamide, reduction routes

37 questions on Preparation of amines: Gabriel, Hofmann bromamide, reduction routes from the Amines and Aromatic Nitrogen Compounds chapter: 8 NEET level, 14 JEE Main, 15 JEE Advanced. Each one opens with its answer and solution.

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The Gabriel phthalimide synthesis can be used to prepare which class of amines? NEET level
Acetamide, CH3CONH2, is treated with Br2 + NaOH (Hofmann bromamide degradation). The organic product is: NEET level
Nitrobenzene is heated with Sn/HCl and the mixture is then made alkaline. The main product is: NEET level
Ethanenitrile, CH3CN, is reduced with LiAlH4. The product is: NEET level
Which amide gives propan-1-amine, CH3CH2CH2NH2, on treatment with Br2 + NaOH? JEE Main level
To obtain ethanamine as the major product from ethyl bromide by ammonolysis, the best condition is: JEE Main level
Which of the following amines cannot be prepared by the Gabriel phthalimide synthesis? JEE Main level
Propanone is treated with NH3 and H2/Ni (reductive amination). The product is: JEE Main level
Benzamide, C6H5CONH2 (12.1 g), is converted to aniline, C6H5NH2, by Br2 + NaOH with 72 percent yield. Using atomic masses H = 1, C = 12, N = 14, O = 16, calcula... JEE Main level
Which of the following reactions give benzylamine, C6H5CH2NH2, as the main organic product? JEE Main level
Nitrobenzene is reduced with LiAlH4 in ether. The main product is: JEE Main level
(R)-2-Methylbutanamide, CH3CH2CH(CH3)CONH2, is treated with Br2 + NaOH. The chiral product is: JEE Advanced level
Which sequence is the best synthesis of 3-bromoaniline from benzene? JEE Advanced level
Propanenitrile is reduced with LiAlH4 to give A. Propanamide is treated with Br2 + NaOH to give B. The correct relation between A and B is: JEE Advanced level
Which statements about the Hofmann bromamide degradation of RCONH2 with Br2 + NaOH are correct? JEE Advanced level
Each of the following compounds is reduced with LiAlH4, and the product is then shaken with C6H5SO2Cl and aqueous KOH. For which compounds is the final mixture ... JEE Advanced level
In the balanced equation for Hofmann bromamide degradation of CH3CONH2 with Br2 and aqueous NaOH, the number of moles of NaOH used per mole of amide and the car... JEE Advanced level
Compound A, C4H9NO, gives amine B with Br2 + NaOH. B on treatment with NaNO2/HCl gives propan-2-ol with evolution of N2. A is: JEE Advanced level
Which of the following amines cannot be prepared by the Gabriel phthalimide synthesis? NEET level
Acetamide, CH3CONH2, is warmed with Br2 + NaOH (Hofmann bromamide degradation). The organic product is NEET level
Nitrobenzene is heated with Sn/HCl and the mixture is then made alkaline. The main organic product is NEET level
Reduction of ethanenitrile, CH3CN, with LiAlH4 followed by water gives NEET level
A primary amine CH3CH2CH2NH2 can be obtained by Hofmann bromamide degradation of amide P and also by LiAlH4 reduction of nitrile Q. P and Q are respectively JEE Main level
N-Benzylphthalimide is heated with aqueous NaOH in the last step of a Gabriel synthesis of benzylamine. The other organic product is JEE Main level
To obtain ethylamine as the main product from ethyl bromide by ammonolysis, the best condition is JEE Main level
Which of the following reagents does NOT convert nitrobenzene into aniline as the main product? JEE Main level
Nitrobenzene is reduced with Zn and aqueous NH4Cl (neutral medium). The main product is JEE Main level
Cyclohexanone is treated with methylamine and then hydrogenated over Ni (reductive amination). The main product is JEE Main level
Benzamide (C6H5CONH2) of mass 12.1 g is subjected to Hofmann bromamide degradation with Br2 + NaOH and gives aniline in 80% yield. Using atomic masses H = 1, C ... JEE Main level
An amide X (C8H9NO) undergoes Hofmann bromamide degradation to give amine Y. When Y is treated with NaNO2 / dil. HCl at 273-278 K, nitrogen gas is evolved vigor... JEE Advanced level
Which reagent sequence converts CH3CH2Br into propan-1-amine, CH3CH2CH2NH2? JEE Advanced level
Assertion: Aniline cannot be synthesised by the Gabriel phthalimide method starting from bromobenzene. Reason: The C-Br bond in bromobenzene has partial double ... JEE Advanced level
Assertion: Hofmann bromamide degradation of an optically active amide R-CONH2 in which R is chiral at the carbon attached to C=O gives an amine of retained conf... JEE Advanced level
Which of the following amines can be prepared from a suitable alkyl halide by the Gabriel phthalimide synthesis (potassium phthalimide, then hydrolysis or hydra... JEE Advanced level
On reduction with LiAlH4 (followed by water), which of the following give a PRIMARY amine? JEE Advanced level
For the Hofmann bromamide degradation, using the balanced equation RCONH2 + Br2 + 4NaOH arrow RNH2 + Na2CO3 + 2NaBr + 2H2O, which statements are correct? JEE Advanced level
Which reagent / main product pairs for the reduction of nitrobenzene are correct? JEE Advanced level