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Organic Reaction Mechanisms III: Nucleophilic Substitution

275 questions in 10 topics. 55 NEET level, 110 JEE Main, 110 JEE Advanced. Every question was written for this chapter and solved independently a second time before publication.

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SN1 mechanism, rate, stereochemistry, rearrangement 29

The hydrolysis of (CH3)3C-Br in aqueous acetone follows the SN1 mechanism. Its rate law is
Optically active (S)-3-chloro-3-methylhexane is hydrolysed in aqueous acetone by the SN1 mechanism. The 3-meth...
The SN1 solvolysis of (CH3)3C-Cl is fastest in which of these solvents?
The carbocation intermediate formed in an SN1 reaction is best described as
In aqueous acetone, (C6H5)2CH-Cl solvolyses by SN1. When some LiCl is added to the solution, the observed rate...
For the SN1 hydrolysis of (CH3)3C-Br in aqueous acetone, the concentration of the bromide is tripled and that ...
2-Bromo-3,3-dimethylbutane, CH3-CHBr-C(CH3)3, is heated in ethanol with no added base. The major substitution ...
2-Bromo-3-methylbutane, (CH3)2CH-CHBr-CH3, is warmed in water. The main alcohol obtained is
All 29 questions on this topic

SN1 vs SN2: substrate, nucleophile, solvent, leaving group 81

SN2 mechanism, rate, stereochemistry, steric effects 28

Organic Reaction Mechanisms III: Nucleophilic Substitution

SN1 mechanism, rate, stereochemistry, rearrangement 29

SN1 vs SN2: substrate, nucleophile, solvent, leaving group 81

SN2 mechanism, rate, stereochemistry, steric effects 28

Neighbouring group participation 27

Nucleophilic aromatic substitution and benzyne 27

Reactions of ethers and epoxides 28

SN1 vs SN2 preference and rate order for drawn substrates 13

Stereochemical outcome of substitution on drawn chiral substrates 14

SN1 rearrangement and neighbouring group participation in drawn substrates 14

Epoxide and ether cleavage regiochemistry on drawn structures 14