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MolSynapse / Question bank / Organic Reaction Mechanisms III: Nucleophilic Substitution / SN2 mechanism, rate, stereochemistry, steric effects
NEET levelSingle correct optionDifficulty 1 of 3o3058

Which of the following alkyl bromides reacts fastest with in dry acetone by the mechanism?

  1. A
  2. B
  3. C
  4. D

Answer: B

SN2 rate falls with crowding at the reacting carbon: methyl primary secondary tertiary. Methyl bromide has only three hydrogens around the carbon, so backside attack is easiest.
Practice Organic Reaction Mechanisms III: Nucleophilic Substitution More on SN2 mechanism, rate, stereochemistry, steric effects

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