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JEE Advanced levelSingle correct optionDifficulty 3 of 3el160

Drug P binds to a receptor site and produces the same response as the natural messenger. Drug Q binds to the same receptor site but produces no response. Which statement is correct?

  1. AP is an antagonist; Q is an agonist and enhances the messenger action
  2. BBoth are agonists but Q has lower potency, so it triggers the response
  3. CP is an enzyme inhibitor and Q is an enzyme activator
  4. DP is an agonist; Q is an antagonist and blocks the natural messenger from binding

Answer: D

A drug that mimics the messenger and triggers the response is an agonist. One that occupies the receptor without triggering the response is an antagonist, and it blocks access of the natural messenger. Receptors are not enzymes, so the last option is wrong.
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