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JEE Advanced levelSingle correct optionDifficulty 3 of 3el159

According to the standard NCERT treatment, penicillin G is effective mainly against Gram-positive bacteria and kills them, while ofloxacin acts against both Gram-positive and Gram-negative bacteria and kills them, chloramphenicol acts against both groups but only stops their growth. Which of the following is correctly described as a broad-spectrum bactericidal antibiotic?

  1. AOfloxacin
  2. BPenicillin G
  3. CChloramphenicol
  4. DNone of these

Answer: A

Broad-spectrum means active against both Gram-positive and Gram-negative bacteria, and bactericidal means the cells are killed. Ofloxacin meets both conditions, penicillin G is narrow-spectrum, and chloramphenicol is only bacteriostatic.
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