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JEE Main levelSingle correct optionDifficulty 2 of 3el016

Cimetidine reduces the secretion of acid in the stomach by preventing histamine from binding to its receptors in the stomach wall. Cimetidine is therefore best described as

  1. Aan agonist of the histamine receptor
  2. Ba base that neutralises hydrochloric acid already present
  3. Ca receptor antagonist (antihistamine) at the stomach receptors
  4. Dan allosteric activator of an enzyme

Answer: C

The drug occupies the receptor and prevents histamine from binding, so no signal for acid secretion is sent. A molecule that blocks a receptor without activating it is an antagonist. It does not neutralise acid chemically.
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