NEET levelSingle correct optionDifficulty 1 of 3nc235
The amide shown is treated with BrX2 and aqueous NaOH (Hofmann bromamide reaction). Which structure is the product?
AStructure A
BStructure B
CStructure C
DStructure D
Answer: B
The amide shown is propanamide. In the Hofmann bromamide reaction the carbonyl carbon is lost as carbonate and the alkyl group migrates to nitrogen, giving a primary amine with one carbon fewer. Propanamide gives ethylamine.