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JEE Advanced levelSingle correct optionDifficulty 3 of 3el024

Sulphanilamide, , resembles p-aminobenzoic acid, a substrate used by bacteria to make folic acid. Which description of sulphanilamide is correct?

  1. AIt is an allosteric inhibitor and belongs to the class of barbiturates
  2. BIt is a receptor agonist and belongs to the class of antihistamines
  3. CIt is a competitive inhibitor of the bacterial enzyme and belongs to the chemical-structure class of sulphonamides
  4. DIt is an irreversible inhibitor that works because it differs completely from the substrate

Answer: C

Its structural resemblance to the substrate lets it enter the active site and compete with p-aminobenzoic acid, which is competitive inhibition. The SO2NH2 unit places it among the sulphonamides by chemical structure. The other options contradict this.
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