A double-stranded DNA contains the strand $5^{'}$ -GATTACAGC- $3^{'}$ fully paired with its complementary strand. Taking A-T pairs to have 2 hydrogen bonds and G-C pairs to have 3, how many hydrogen bonds hold the two strands together? (Give an integer.)

Numerical answer type, tolerance 0.5.

Answer: 22

The strand GATTACAGC has 4 G or C bases (positions 1, 6, 8, 9) and 5 A or T bases. Each base pairs with one partner, so there are 4 G-C pairs and 5 A-T pairs. Hydrogen bonds =

4 \times 3 + 5 \times 2 = 22

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