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JEE Main levelSingle correct optionDifficulty 2 of 3bm149

Bacterial DNA labelled with in both strands is allowed to replicate semi-conservatively for exactly two rounds in a medium containing only . The four resulting DNA duplexes are

  1. Aall four with one strand and one strand
  2. Bone with both strands and three with both strands
  3. Ctwo with one strand and one strand, and two with both strands
  4. Dall four with both strands

Answer: C

After round 1 both duplexes are hybrids (15N/14N). In round 2 each hybrid separates: the heavy strand makes a hybrid and the light strand makes a fully light duplex. This gives 2 hybrids and 2 fully 14N duplexes.
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