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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3bm137

Select the correct statements about the effect of temperature and pH on enzymes.

ABetween $0^{\circ} C$ and the optimum temperature the rate rises with temperature.
BAbove the optimum temperature the activity drops because the enzyme is denatured.
CPepsin (stomach) and trypsin (small intestine) have the same optimum pH of about 7.
DDenaturation breaks the peptide bonds of the primary structure.

Answer: A, B

Below the optimum, rate rises with temperature. Above it, denaturation destroys the 2nd and 3rd structure of the protein. Pepsin works in acidic medium and trypsin in alkaline, so they differ. Denaturation does not cleave peptide bonds.

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