MolSynapsequestion bank
MolSynapse / Question bank / Reduction, Oxidation and Hydrolysis in Organic Chemistry / Periodic acid and lead tetraacetate cleavage
JEE Advanced levelOne or more correct optionsDifficulty 3 of 3ro200

Which of the following compounds are cleaved by under mild conditions?

  1. A2,3-dimethylbutane-2,3-diol
  2. Bpropane-1,3-diol
  3. C2-hydroxypropanoic acid
  4. Dpropane-1,2,3-triol

Answer: A, C, D

Pinacol, lactic acid (alpha-hydroxy acid) and glycerol all contain adjacent oxygen-bearing carbons. Propane-1,3-diol has its OH groups separated by a CH2, so no cyclic periodate ester forms and it is not cleaved.
Practice Reduction, Oxidation and Hydrolysis in Organic Chemistry More on Periodic acid and lead tetraacetate cleavage
Previous questionNext question

More questions on Periodic acid and lead tetraacetate cleavage