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JEE Main levelSingle correct optionDifficulty 2 of 3ro156

Consider hydrolysis with water: ethanoyl chloride (I), ethanoic anhydride (II), ethyl ethanoate (III), ethanamide (IV). The correct order of ease of hydrolysis is

  1. A
  2. B
  3. C
  4. D

Answer: D

Reactivity toward nucleophilic acyl substitution follows the leaving-group ability and the lack of resonance donation to the carbonyl: is the best leaving group, then carboxylate, then alkoxide, then the amide nitrogen (best donor). The order is acyl chloride anhydride ester amide.
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