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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3o4212

Which statements about Hofmann elimination (quaternary ammonium hydroxide, heated) are correct?

  1. AIt is an E2 reaction with anti-periplanar elimination.
  2. BIt gives mainly the more substituted alkene, as in Saytzeff's rule.
  3. C/ converts the quaternary iodide into the hydroxide.
  4. DThe leaving group is a neutral tertiary amine.

Answer: A, C, D

Hofmann elimination is E2, with as the neutral leaving group, and the hydroxide is made from the iodide with moist (AgI precipitates). The bulky group and poor leaving ability direct elimination to the least hindered hydrogen, giving the less substituted alkene, so statement 2 is wrong.
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