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JEE Advanced levelSingle correct optionDifficulty 3 of 3el217

Three drugs are described. K: raises the level of noradrenaline by inhibiting the enzyme that degrades it. L: a derivative of barbituric acid that induces sleep. M: a mild tranquiliser used to relieve tension and also to treat depression and hypertension. Which assignment is correct?

  1. AK = equanil; L = iproniazid; M = luminal
  2. BK = iproniazid; L = luminal; M = equanil (meprobamate)
  3. CK = iproniazid; L = equanil; M = luminal
  4. DK = luminal; L = iproniazid; M = equanil

Answer: B

An MAO inhibitor that raises noradrenaline is iproniazid (or phenelzine). A barbituric acid derivative that acts as a hypnotic is luminal (a barbiturate). A mild tranquiliser used for tension, depression and hypertension is equanil (meprobamate). Hence K-iproniazid, L-luminal, M-equanil.
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