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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3el096

Select the correct statements about early chemotherapeutic agents and penicillins.

  1. ASalvarsan, an arsenic compound made by Paul Ehrlich, was used against syphilis
  2. BPenicillin was first isolated from a Streptomyces bacterium
  3. CProntosil is converted in the body to sulphanilamide, which is the active antibacterial agent
  4. DAmpicillin is a semisynthetic modification of penicillin

Answer: A, C, D

Prontosil is a prodrug of sulphanilamide, Salvarsan treated syphilis and ampicillin is a semisynthetic penicillin. Fleming obtained penicillin from the mould Penicillium, not Streptomyces.
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