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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3el093

A patient has hay fever and also suffers from excess stomach acid. Select the correct statements.

  1. ATerfenadine blocks the same type of receptor as ranitidine
  2. BCimetidine and ranitidine neutralise the hydrochloric acid already present, as magnesium hydroxide does
  3. CRanitidine reduces acidity because it prevents histamine from acting on the receptors of the stomach wall
  4. DBrompheniramine, an H1 antagonist, is suitable for the hay fever symptoms but not for the acidity

Answer: C, D

Acid secretion is mediated by H2 receptors, blocked by ranitidine and cimetidine, which reduce secretion rather than neutralising acid. Allergy symptoms involve H1 receptors, blocked by brompheniramine and terfenadine.
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