JEE Advanced levelSingle correct optionDifficulty 3 of 3bm196
Consider the tetrapeptide Ala-Thr-Ile-Gly (N-terminal to C-terminal) and suppose each stereocentre in the chain may independently have either configuration. Threonine and isoleucine each have two stereocentres (alpha and beta carbons). Counting no symmetry, the total number of stereoisomers of this tetrapeptide is
A16
B64
C32
D8
Answer: C
Stereocentres: Ala 1, Thr 2, Ile 2, Gly 0 = 5. Number of stereoisomers =25=32.