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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3bm108

Which statements about secondary structures of proteins are correct?

  1. AIn the alpha-helix the hydrogen bonds are perpendicular to the helix axis.
  2. BBoth structures are held mainly by disulfide bridges.
  3. CIn the beta-pleated sheet, hydrogen bonds join C=O and N-H groups of neighbouring strands.
  4. DIn the alpha-helix, hydrogen bonds join backbone groups of the same chain.

Answer: C, D

Secondary structure arises from backbone hydrogen bonds: within one coil for the alpha-helix (bonds run roughly parallel to the axis) and between side-by-side strands for the sheet. Disulfide bridges belong to tertiary structure.
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