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Itai-itai disease, which causes severe bone and joint pain and kidney damage, is caused by contamination of water and food with:

  1. Afluoride
  2. Bnitrate
  3. Ccadmium
  4. Dmercury

Answer: C

Itai-itai disease was traced to cadmium in water and rice. Mercury (as methylmercury) causes Minamata disease, so it is not the answer.
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