JEE Main levelSingle correct optionDifficulty 2 of 3el212
Assertion (A): Iproniazid and phenelzine are used as antidepressant drugs.
Reason (R): They inhibit the enzyme that catalyses the degradation of noradrenaline, so the neurotransmitter stays at a higher level.
ABoth A and R are true, and R is the correct explanation of A
BBoth A and R are true, but R is not the correct explanation of A
CA is true but R is false
DA is false but R is true
Answer: A
Iproniazid and phenelzine are monoamine oxidase (MAO) inhibitors. By inhibiting the enzyme that breaks down noradrenaline, they raise its level and so relieve depression. R explains A.