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JEE Advanced levelSingle correct optionDifficulty 3 of 3el106

A depressed patient is given a drug X that raises the effective level of noradrenaline in the body. Which description of X is consistent with the mechanism of drugs such as iproniazid?

  1. AIt inhibits the enzymes that break down noradrenaline, so the neurotransmitter stays active longer
  2. BIt destroys the receptors on which noradrenaline acts
  3. CIt blocks the release of noradrenaline from nerve endings
  4. DIt neutralises noradrenaline as an antacid would

Answer: A

Low noradrenaline causes low signal-sending activity and depression. Iproniazid and phenelzine inhibit the enzymes that catalyse noradrenaline degradation, so its level stays high.
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