JEE Advanced levelSingle correct optionDifficulty 3 of 3el089
Four unknown drugs P, Q, R and S have these properties. P: analgesic and antipyretic, not anti-clotting, has a phenolic -OH and an amide group. Q: analgesic, antipyretic and inhibits blood clotting, has an ester and a carboxylic acid group. R: narcotic, with one free hydroxyl group because the phenolic -OH is converted to -OCH3, used as a cough suppressant. S: narcotic, no free hydroxyl group, highly habit forming. The correct identification is
AP = paracetamol, Q = aspirin, R = codeine, S = heroin
BP = paracetamol, Q = aspirin, R = morphine, S = heroin
CP = paracetamol, Q = aspirin, R = heroin, S = codeine
DP = aspirin, Q = paracetamol, R = codeine, S = heroin
Answer: A
P has -OH and -NHCOCH3, so it is paracetamol. Q has -COOH and -OCOCH3, so it is aspirin. R, with the phenolic -OH methylated, is codeine, and S, with both -OH groups acetylated, is heroin. Morphine would have two free -OH groups.