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JEE Advanced levelOne or more correct optionsDifficulty 3 of 3bm165

Which of the following base compositions (percent of total bases) can belong to a double-stranded DNA?

  1. AA = 28, T = 28, G = 22, C = 22
  2. BA = 30, T = 20, G = 25, C = 25
  3. CA = 18, T = 18, G = 32, C = 32
  4. DA = 26, T = 24, G = 26, C = 24

Answer: A, C

By Chargaff rule in a duplex, A = T and G = C. Only the first and third satisfy this, and each sums to 100. The second and fourth have A not equal to T.
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